Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28097037 | 0.89 | MEN1 (0.52) | MEN1KMT2AL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL6667180 | 0.83 | PPARG (0.58) | MEN1KMT2AL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL27638666 | 0.83 | KMT2A (0.61) | MEN1KMT2AL3MBTL1ALDH1A1CA12 | |
| SCHEMBL286684 | 0.82 | IDO1 (0.58) | MEN1KMT2AL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL10827236 | 0.81 | IDO1 (0.56) | MEN1KMT2AL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL1030014 | 0.81 | IDO1 (0.56) | MEN1KMT2AL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL18398576 | 0.81 | IDO1 (0.56) | MEN1KMT2AL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL31072414 | 0.81 | IDO1 (0.56) | MEN1KMT2AL3MBTL1IDO1ALDH1A1 | |
| SCHEMBL9271624 | 0.81 | LMNA (0.57) | MEN1KMT2AIDO1ALDH1A1TSHR | |
| SCHEMBL9330680 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1TSHRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118948925-A | A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application | 广西仙手棋药业科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118948925-A | A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application | 广西仙手棋药业科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-117959276-A | A composition extracted from Celastrus orbiculatus plant for treating cancer, and its preparation method and application | 广西仙手棋药业科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-106110116-A | Chinese medicine composition containing Radix Helicteris and preparation method thereof | 广西万德药业有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-106075229-A | A kind of Chinese medicinal composition preparation treating anemopyretic cold | 广西万德药业有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105999166-A | Formula and preparation method of traditional Chinese medicine for treating chilblain | 三峡大学 | 2016-10-12 | — | — | CN | disclosed |
| CN-105998977-A | Anti-cold medicine preparation | 广西万德药业有限公司 | 2016-10-12 | — | — | CN | disclosed |