Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28528599 | 0.98 | CHRM2 (0.33) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL28101497 | 0.89 | HRH2 (0.35) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL28112848 | 0.89 | HRH2 (0.35) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL27875035 | 0.83 | — | — | |
| SCHEMBL26628945 | 0.81 | ENO1 (0.32) | MEN1KMT2A | |
| SCHEMBL26094973 | 0.81 | ENO1 (0.32) | MEN1KMT2A | |
| SCHEMBL26094335 | 0.81 | ENO1 (0.32) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28782905 | 0.80 | ENO1 (0.32) | MEN1KMT2A | |
| SCHEMBL7405162 | 0.79 | CA12 (0.35) | CHRM2MEN1CYP2D6KMT2ACHRM1 | |
| SCHEMBL7234663 | 0.79 | ALDH1A1 (0.43) | CHRM2MEN1CYP2D6KMT2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188027-A | Heteroaromatic analog derivative and the application in medicine thereof | 广东东阳光药业有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-102300862-B | Compounds useful as inhibitors of ATR kinase | 沃泰克斯药物股份有限公司 | 2016-11-23 | — | — | CN | disclosed |