Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813391 | 0.90 | CYP1A2 (0.64) | CYP1A2ALDH1A1MAPTRAD51KDM4E | |
| SCHEMBL2808736 | 0.88 | CYP1A2 (0.65) | CYP1A2ALDH1A1MAPTRAD51KDM4E | |
| SCHEMBL2811947 | 0.87 | CYP1A2 (0.64) | CYP1A2ALDH1A1MAPTRAD51KDM4E | |
| SCHEMBL2814707 | 0.85 | MAPT (0.62) | CYP1A2ALDH1A1MAPTKDM4EGAA | |
| SCHEMBL2813628 | 0.85 | CYP1A2 (0.65) | CYP1A2ALDH1A1MAPTRAD51KDM4E | |
| SCHEMBL2035745 | 0.84 | NSD2 (0.74) | ALDH1A1MAPTNSD2KDM4ESMN1; SMN2 | |
| SCHEMBL4605841 | 0.81 | CYP1A2 (0.61) | CYP1A2ALDH1A1MAPTRAD51KDM4E | |
| SCHEMBL2807577 | 0.81 | FAAH (0.52) | CYP1A2ALDH1A1MAPTRAD51KDM4E | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.80 | ALDH1A1 (0.76) | CYP1A2ALDH1A1MAPTRAD51KDM4E | |
| SCHEMBL8063648 | 0.80 | ALDH1A1 (0.82) | CYP1A2ALDH1A1MAPTRAD51KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | CYP1A2 535/4885ALDH1A1 401/4885MAPT 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.