Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736667 | 0.84 | CHRM2 (0.35) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL2736669 | 0.84 | CHRM2 (0.35) | CHRM2CHRM4CHRM1CHRM3LMNA | |
| SCHEMBL27724060 | 0.83 | POLB (0.42) | ALDH1A1POLB | |
| SCHEMBL27702947 | 0.82 | ALDH1A1 (0.39) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28266022 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27825234 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28172933 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL27904549 | 0.81 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL26558297 | 0.81 | KMT2A (0.39) | CYP2D6KMT2AMEN1TAAR1AOC3 | |
| SCHEMBL27575990 | 0.78 | LMNA (0.35) | LMNAFFAR1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108892661-A | Therapeutic compounds and composition | 艾克赛特赫拉制药有限责任公司 | 2018-11-27 | — | — | CN | disclosed |
| CN-106029064-A | Therapeutic compounds and compositions | 艾克赛特赫拉制药有限责任公司 | 2016-10-12 | — | — | CN | disclosed |