SCHEMBL28101978

SCHEMBL28101978

N[C@H](CO)Cc1cc[c]cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.44
SLC6A4 P31645 4/20 0.41
PCNA P12004 1/20 0.39
LIG1 P18858 1/20 0.39
ANPEP P15144 3/20 0.39
ENPEP Q07075 2/20 0.36
TAAR1 Q96RJ0 3/20 0.34
SLC6A2 P23975 1/20 0.34
MMP2 P08253 1/20 0.33
OPRK1 P41145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
L-Phenylalaninol SCHEMBL27430394 0.79 EPHX1 (0.73) EPHX1SLC6A4ANPEPTAAR1SLC6A2
SCHEMBL9047050 0.79 TRPA1 (0.34)
SCHEMBL28428070 0.79 EPHX1 (0.36) EPHX1SLC6A4ANPEPTAAR1SLC6A2
SCHEMBL28101977 0.78 EPHX1 (0.47) EPHX1SLC6A4PCNALIG1ANPEP
SCHEMBL1068785 0.77 CYP3A4 (0.42)
SCHEMBL3034215 0.77 CYP3A4 (0.42)
L-Phenylalaninol SCHEMBL87692 0.76 EPHX1 (0.76) EPHX1SLC6A4ANPEPTAAR1SLC6A2
L-Phenylalaninol SCHEMBL81769 0.76 EPHX1 (0.76) EPHX1SLC6A4ANPEPTAAR1SLC6A2
L-Phenylalaninol SCHEMBL177073 0.76 EPHX1 (0.76) EPHX1SLC6A4ANPEPTAAR1SLC6A2
L-Phenylalaninol SCHEMBL2521 0.76 EPHX1 (0.76) EPHX1SLC6A4ANPEPTAAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899526-A Cytotoxic peptides and conjugates thereof 诺华股份有限公司 2016-08-24 CN disclosed