Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 9/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469717 | 0.83 | MRGPRX4 (0.74) | MRGPRX4SLC6A4HTR6FFAR1FFAR4 | |
| SCHEMBL693190 | 0.83 | MRGPRX4 (0.51) | MRGPRX4SLC6A4HTR6FFAR1FFAR4 | |
| SCHEMBL9035362 | 0.83 | MRGPRX4 (0.52) | MRGPRX4SLC6A4HTR6FFAR1FFAR4 | |
| SCHEMBL22480554 | 0.81 | MRGPRX4 (1.00) | MRGPRX4SLC6A4GRM5 | |
| SCHEMBL985802 | 0.81 | EGFR (0.47) | MRGPRX4MAOB | |
| SCHEMBL1446254 | 0.79 | HPGD (0.46) | MRGPRX4MAOB | |
| SCHEMBL22480929 | 0.79 | MRGPRX4 (0.68) | MRGPRX4SLC6A4HTR6FFAR1FFAR4 | |
| SCHEMBL22469778 | 0.78 | MRGPRX4 (0.76) | MRGPRX4SLC6A4HTR6PDCD1CD274 | |
| SCHEMBL31568445 | 0.78 | MRGPRX4 (0.76) | MRGPRX4SLC6A4HTR6PDCD1CD274 | |
| SCHEMBL14854689 | 0.78 | MRGPRX4 (0.76) | MRGPRX4SLC6A4HTR6FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-B | Cyano-quinoline derivatives | 天津和美生物技术有限公司 | 2016-09-07 | — | — | CN | claimed |