Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27584712 | 0.84 | SMN1; SMN2 (0.43) | ALDH1A1MAPK1TDP1L3MBTL1HPGD | |
| SCHEMBL8665449 | 0.79 | TDP1 (0.43) | ALDH1A1TDP1ERN1MAPTTP53 | |
| SCHEMBL28234701 | 0.79 | MAPK1 (0.41) | ALDH1A1MAPK1TDP1L3MBTL1ERN1 | |
| SCHEMBL26363682 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MAPK1TDP1L3MBTL1ERN1 | |
| SCHEMBL18068141 | 0.76 | DGAT1 (0.36) | ALDH1A1MAPK1TDP1L3MBTL1ERN1 | |
| SCHEMBL12214099 | 0.76 | KDM4E (0.41) | ALDH1A1MAPK1TDP1L3MBTL1ERN1 | |
| SCHEMBL16048590 | 0.76 | HPGD (0.38) | ALDH1A1HTR2ASLC6A4KCNH2MAPK1 | |
| SCHEMBL10467231 | 0.75 | MAPK1 (0.58) | ALDH1A1MAPK1TDP1L3MBTL1ERN1 | |
| SCHEMBL14725300 | 0.74 | TSHR (0.46) | ALDH1A1TDP1L3MBTL1ERN1GAA | |
| SCHEMBL263669 | 0.72 | MAPT (0.47) | ALDH1A1HTR2ASLC6A4KCNH2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117192-A | The synthetic method that a kind of En Gelie is clean | 甘肃成纪生物药业有限公司 | 2016-11-16 | — | — | CN | disclosed |