Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 4/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F12 | P00748 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28102590 | 0.82 | MAPT (0.50) | ALOX15HTTALDH1A1MAPTGAA | |
| SCHEMBL28102515 | 0.82 | RXFP1 (0.50) | HTTALDH1A1MAPTGAAVNN1 | |
| SCHEMBL11750033 | 0.79 | PBRM1 (0.50) | PBRM1ALOX15HTTALDH1A1ATM | |
| SCHEMBL27602501 | 0.74 | PDGFRB (0.54) | ALDH1A1ATML3MBTL1MAPTGAA | |
| SCHEMBL28102456 | 0.73 | F2 (0.44) | PBRM1HTTALDH1A1MAPTGAA | |
| SCHEMBL28239 | 0.72 | CHRNA7 (0.48) | ALOX15HTTALDH1A1ATMMAPT | |
| SCHEMBL1516765 | 0.72 | MAPT (0.61) | PBRM1ALOX15HTTALDH1A1MAPT | |
| Benzophenone SCHEMBL6678679 | 0.72 | ALDH1A1 (0.82) | PBRM1ALDH1A1ATMTDP1L3MBTL1 | |
| Benzophenone SCHEMBL28888896 | 0.72 | ALDH1A1 (0.82) | PBRM1ALDH1A1ATMTDP1L3MBTL1 | |
| SCHEMBL17008169 | 0.71 | AKR1C3 (0.63) | ALDH1A1ATMTDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-B | Cyano-quinoline derivatives | 天津和美生物技术有限公司 | 2016-09-07 | — | — | CN | disclosed |