Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | CATSPER1 | Q8NEC5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28102587 | 0.82 | PRSS1 (0.51) | HPGDPRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL305751 | 0.78 | GLA (0.51) | PBRM1GLAHPGDKMT2AMAPT | |
| SCHEMBL28102448 | 0.73 | PBRM1 (0.44) | F2F10F12F7F3 | |
| SCHEMBL11750033 | 0.72 | PBRM1 (0.50) | PBRM1KMT2AMAPTGAAPOLB | |
| SCHEMBL674194 | 0.70 | MAPT (0.53) | PBRM1BLMKMT2AMAPTGAA | |
| SCHEMBL30821243 | 0.70 | MAPT (0.53) | PBRM1BLMKMT2AMAPTGAA | |
| Benzamidine SCHEMBL2781806 | 0.68 | F2 (0.84) | F2F10F12F7F3 | |
| SCHEMBL19857474 | 0.68 | ALDH1A1 (0.48) | HPGDKMT2APOLBHSD17B10ALDH1A1 | |
| SCHEMBL28226892 | 0.68 | ALDH1A1 (0.58) | PBRM1GLAKMT2AMAPTGAA | |
| SCHEMBL6791689 | 0.67 | PBRM1 (0.51) | F2F10F12F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-B | Cyano-quinoline derivatives | 天津和美生物技术有限公司 | 2016-09-07 | — | — | CN | disclosed |