Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.72 |
| ▸ | F10 | P00742 | 3/20 | 0.60 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308749 | 0.88 | HCAR3 (0.77) | HCAR3DEGS1RAB9AKMT2AKDM4E | |
| SCHEMBL2664544 | 0.84 | HCAR3 (1.00) | HCAR3DEGS1RAB9AKMT2AKDM4E | |
| SCHEMBL6515262 | 0.84 | HCAR3 (0.70) | HCAR3DEGS1RAB9AKMT2AKDM4E | |
| SCHEMBL28102586 | 0.83 | DEGS1 (0.69) | F10DEGS1RAB9AKMT2ANPC1 | |
| SCHEMBL2664558 | 0.82 | HCAR3 (0.68) | HCAR3F10DEGS1RAB9AKMT2A | |
| SCHEMBL2664535 | 0.80 | HCAR3 (0.69) | HCAR3DEGS1RAB9AKMT2AKDM4E | |
| SCHEMBL30354834 | 0.80 | HCAR3 (0.69) | HCAR3DEGS1RAB9AKMT2AKDM4E | |
| SCHEMBL14505713 | 0.79 | HCAR3 (0.72) | HCAR3DEGS1RAB9AKMT2AKDM4E | |
| SCHEMBL29220747 | 0.78 | HCAR3 (0.71) | HCAR3DEGS1RAB9AKMT2AKDM4E | |
| SCHEMBL29519035 | 0.78 | DEGS1 (0.82) | HCAR3DEGS1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102933578-B | Cyano-quinoline derivatives | 天津和美生物技术有限公司 | 2016-09-07 | — | — | CN | disclosed |