SCHEMBL28102499

SCHEMBL28102499

C=CC(=O)Nc1ccc(OC)cc1OC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.69
ALDH1A1 P00352 3/20 0.65
CYP1A1 P04798 1/20 0.60
CYP1A2 P05177 1/20 0.60
CYP1B1 Q16678 1/20 0.60
TGM2 P21980 1/20 0.59
HPGD P15428 1/20 0.59
MAPT P10636 4/20 0.58
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.57
LMNA P02545 1/20 0.57
AHR P35869 1/20 0.57
EGFR P00533 1/20 0.57
KDM4E B2RXH2 1/20 0.55
GLA P06280 1/20 0.55
HSD17B10 Q99714 1/20 0.55
TSHR P16473 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
MEN1 O00255 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28835016 0.88 NPSR1 (0.63) GAAALDH1A1TGM2HPGDMAPT
SCHEMBL2044824 0.86 GAA (0.53) GAAALDH1A1CYP1A1CYP1A2CYP1B1
SCHEMBL25648912 0.84 TGM2 (0.59) GAAALDH1A1TGM2NPC1RAB9A
SCHEMBL2094903 0.84 GAA (0.69) GAAALDH1A1CYP1A1CYP1A2CYP1B1
SCHEMBL11329599 0.83 TGM2 (0.58) GAAALDH1A1TGM2HPGDMAPT
SCHEMBL31596022 0.83 GAA (0.54) GAAALDH1A1TGM2MAPTNPC1
SCHEMBL19958218 0.83 TGM2 (0.58) GAAALDH1A1TGM2MAPTNPC1
SCHEMBL28447726 0.83 LPAR1 (0.52) GAAALDH1A1TGM2MAPTNPC1
SCHEMBL6475098 0.82 ALDH1A1 (0.71) GAAALDH1A1CYP1A1CYP1A2CYP1B1
SCHEMBL22895498 0.82 CA12 (0.54) GAAALDH1A1RAB9ALMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955381-A Pyrazole compound as well as preparation method and application thereof 赣南师范大学 2024-11-15 CN claimed
CN-118955381-A Pyrazole compound as well as preparation method and application thereof 赣南师范大学 2024-11-15 CN disclosed
CN-106008480-A Quinazoline compound containing cinnamamide structure and preparation method and application thereof 江西科技师范大学 2016-10-12 CN disclosed