SCHEMBL28102736

SCHEMBL28102736

COc1c(Cl)cccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 4/20 0.45
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 1/20 0.41
NOTUM Q6P988 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 3/20 0.40
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
CTSA P10619 1/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384 0.84 USP2 (0.52) ALDH1A1NPC1RAB9APOLBMAPT
SCHEMBL28827502 0.82 LMNA (0.45) ALDH1A1NPC1RAB9ALMNACES2
Bicarbonate SCHEMBL31648960 0.82 USP2 (0.51) ALDH1A1NPC1RAB9APOLBMAPT
Bicarbonate SCHEMBL1969232 0.82 USP2 (0.51) ALDH1A1NPC1RAB9APOLBMAPT
Methoxymethane SCHEMBL28122245 0.82 USP2 (0.51) ALDH1A1NPC1RAB9APOLBMAPT
Benzene SCHEMBL28180511 0.81 USP2 (0.50) ALDH1A1NPC1RAB9APOLBMAPT
Acetic Acid SCHEMBL8064561 0.81 USP2 (0.50) ALDH1A1NPC1RAB9APOLBMAPT
SCHEMBL44517 0.81 LMNA (0.57) ALDH1A1NPC1RAB9APOLBMAPT
Carbamic Acid SCHEMBL3710620 0.80 NPC1 (0.49) ALDH1A1NPC1RAB9APOLBMAPT
SCHEMBL3454583 0.80 TSHR (0.56) ALDH1A1NPC1RAB9ALMNACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146288-A A kind of post processing separation method of aromatic hydroxy carboxy acid's intermediate 3,6 dichloro 2 methoxybenzoic acid 陈云华 2016-11-23 CN disclosed