Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 17/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761733 | 0.80 | MAOB (0.61) | NPC1MAPTRAB9ATP53IDO1 | |
| SCHEMBL70456 | 0.79 | MAOB (0.76) | NPC1MAPTRAB9ATP53IDO1 | |
| SCHEMBL6345667 | 0.78 | KMT2A (0.61) | NPC1MAPTRAB9AHPGDHSD17B10 | |
| SCHEMBL87682 | 0.77 | MAOB (0.58) | NPC1MAPTRAB9ATP53IDO1 | |
| SCHEMBL1299217 | 0.77 | MAOB (0.58) | NPC1MAPTRAB9AMAOBMAOA | |
| SCHEMBL27822584 | 0.77 | MAOB (0.73) | NPC1MAPTRAB9ATP53IDO1 | |
| SCHEMBL2301535 | 0.77 | MAOB (0.58) | NPC1MAPTRAB9ATP53IDO1 | |
| SCHEMBL13655497 | 0.77 | MAOB (0.62) | NPC1MAPTRAB9ATP53IDO1 | |
| Hydrochloric Acid SCHEMBL87683 | 0.77 | MAOB (0.73) | NPC1MAPTRAB9ATP53IDO1 | |
| SCHEMBL1919254 | 0.76 | MAPT (0.58) | NPC1MAPTRAB9AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110225753-A | The method for being used to prepare 5- phenoxy group -1 (3H) isobenzofuranone | 金凯生命科学有限责任公司 | 2019-09-10 | — | — | CN | claimed |
| CN-106316999-B | A kind of preparation method and application of two ketoximes derivatives of benzofuran -2,3- | 江苏强盛功能化学股份有限公司 | 2019-01-08 | — | — | CN | claimed |
| CN-105518003-B | process for the preparation of fluoxastrobin | 爱利思达生命科学株式会社 | 2018-02-13 | — | — | CN | claimed |
| CN-106316999-A | Preparing method and application for coumarone- 2,3- diketone oxime derivative | 江苏强盛功能化学股份有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-104245685-B | The production method of (acetylene-1,2-diyl) double (isobenzofuran-1,3-diketone) | 聂克斯姆化学有限公司 | 2016-09-07 | — | — | CN | claimed |
| CN-106458834-B | Diphenyl carbonate and method for producing same, catalyst and method for producing, recovering and reusing same, and polycarbonate | 三菱化学株式会社 | 2019-10-25 | — | — | CN | disclosed |
| CN-110078725-A | Target compound and its application of ubiquitination degradation GSK-3 β albumen | 中国药科大学 | 2019-08-02 | — | — | CN | disclosed |
| CN-105189508-B | Naphthenic base nitrile Pyrazolopyridine ketone as JANUS kinase inhibitor | 默沙东公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108699383-A | Thermosetting coating compositions | 伊士曼化工公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-107690428-A | process for the preparation of (E) - (5, 6-dihydro-1, 4, 2-dioxazin-3-yl) (2-hydroxyphenyl) methanone O-methyloxime | 爱利思达生命科学株式会社 | 2018-02-13 | — | — | CN | disclosed |
| CN-105518003-B | process for the preparation of fluoxastrobin | 爱利思达生命科学株式会社 | 2018-02-13 | — | — | CN | disclosed |
| CN-106458834-A | Diphenyl carbonate and method for producing same, catalyst and method for producing, recovering and reusing same, and polycarbonate | 三菱化学株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-104245685-B | The production method of (acetylene-1,2-diyl) double (isobenzofuran-1,3-diketone) | 聂克斯姆化学有限公司 | 2016-09-07 | — | — | CN | disclosed |