Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 10/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | NCOR1 | O75376 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.62 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.62 |
| ▸ | PLK1 | P53350 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8171773 | 0.95 | SOAT2 (0.66) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL15675695 | 0.93 | SOAT2 (0.68) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL8582253 | 0.89 | L3MBTL1 (0.62) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL20171243 | 0.89 | MAPT (0.60) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL13997229 | 0.88 | HDAC8 (0.54) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL10441137 | 0.85 | CYP1A2 (0.58) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL6296181 | 0.85 | HDAC4 (0.75) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL517309 | 0.85 | HDAC4 (0.81) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL11328654 | 0.84 | HDAC8 (0.60) | HDAC8HDAC6HDAC2HDAC4HDAC1 | |
| SCHEMBL6669511 | 0.83 | HDAC4 (0.85) | HDAC8HDAC6HDAC2HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008251-A | Preparation method of 2-benzylidene isobutyryl acetanilide | 河南豫辰药业股份有限公司 | 2016-10-12 | — | — | CN | disclosed |