Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103221 | 0.92 | HPGD (0.47) | MAPTIDO1KDM4EALDH1A1LMNA | |
| SCHEMBL28103023 | 0.91 | ALDH1A1 (0.44) | MAPTIDO1KDM4EALDH1A1LMNA | |
| SCHEMBL28103214 | 0.90 | KDM4E (0.53) | MAPTIDO1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28835051 | 0.86 | MAPT (0.53) | MAPTIDO1KDM4EALDH1A1LMNA | |
| SCHEMBL28103002 | 0.84 | KDM4E (0.49) | MAPTTP53KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28103218 | 0.83 | HPGD (0.45) | MAPTIDO1KDM4EALDH1A1LMNA | |
| SCHEMBL28103008 | 0.81 | HPGD (0.43) | MAPTIDO1KDM4EALDH1A1LMNA | |
| SCHEMBL28103004 | 0.79 | KDM4E (0.50) | MAPTKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28103204 | 0.77 | KDM4E (0.51) | MAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29059782 | 0.76 | MAPT (0.52) | MAPTTP53KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045994-A | Perfluoroalkyl indolizine derivative and synthesis method thereof | 上海大学 | 2016-10-26 | — | — | CN | disclosed |