Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30549316 | 0.88 | KMT2A (0.54) | MAPTKMT2AMEN1NPSR1RXFP1 | |
| SCHEMBL29059897 | 0.81 | KDM4E (0.47) | MAPTKMT2AMEN1MAPK1NPSR1 | |
| SCHEMBL28103003 | 0.76 | MAPT (0.45) | MAPTKMT2ALMNATP53KDM4E | |
| SCHEMBL15184982 | 0.73 | MAPT (0.52) | MAPTKMT2AMEN1LMNARAB9A | |
| SCHEMBL29547493 | 0.72 | FNTA (0.54) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL1010096 | 0.72 | RAB9A (1.00) | MAPTKMT2AMEN1LMNAMAPK1 | |
| SCHEMBL29059749 | 0.71 | ALDH1A1 (0.49) | MAPTKMT2AMEN1MAPK1NPSR1 | |
| SCHEMBL29059951 | 0.71 | MAPT (0.48) | MAPTKMT2AMEN1MAPK1NPSR1 | |
| SCHEMBL15172903 | 0.70 | FNTA (0.49) | MAPTKMT2AMEN1NPSR1FNTA | |
| Iodomethane SCHEMBL26988000 | 0.69 | RAB9A (0.92) | MAPTKMT2AMEN1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116640135-A | Preparation method of 3-carbonyl-2-fluoro substituted indolizine compound | 平顶山学院 | 2023-08-25 | — | — | CN | claimed |
| CN-116640135-A | Preparation method of 3-carbonyl-2-fluoro substituted indolizine compound | 平顶山学院 | 2023-08-25 | — | — | CN | disclosed |