⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24816239 | 0.78 | — | — | |
| SCHEMBL28279048 | 0.76 | — | — | |
| SCHEMBL3215267 | 0.76 | — | — | |
| SCHEMBL22520015 | 0.73 | POLB (0.31) | — | |
| SCHEMBL22519854 | 0.73 | HTR2A (0.30) | — | |
| SCHEMBL27545251 | 0.70 | NOS2 (0.30) | — | |
| SCHEMBL29306403 | 0.70 | CYP2D6 (0.33) | — | |
| SCHEMBL27550673 | 0.70 | NOS2 (0.30) | — | |
| SCHEMBL21406445 | 0.69 | — | — | |
| SCHEMBL11649346 | 0.68 | EPHX1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027040-A | Nucleoside compound for treating coronavirus infection and application thereof | 南方科技大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117964624-A | Nucleoside compound with effect of treating viral infection and application thereof | 南方科技大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117777141-A | Nucleoside compound for resisting virus infection and application thereof | 南方科技大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-116370479-B | Use of compound ATV014 in the preparation of a product for the treatment of novel coronavirus infection | 南方科技大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-113735862-B | Nucleoside compound for treating viral infection and application thereof | 南方科技大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-117083271-A | Substituted thiadiazolyl derivatives as DNA polymerase theta inhibitors | 伊迪亚生物科学有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116874490-A | Compound ATV014 or pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof | 南方科技大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-115583954-B | Crystal form of isobutyrate nucleoside compound and preparation method thereof | 深圳安泰维生物医药有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-116370479-A | Use of compound ATV014 in the preparation of a product for the treatment of novel coronavirus infection | 南方科技大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-115583954-A | Crystal form of isobutyrate nucleoside compound and preparation method | 深圳安泰维生物医药有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-113698405-B | Crystal form of nucleoside compound and preparation method thereof | 南方科技大学坪山生物医药研究院 | 2022-09-27 | — | — | CN | disclosed |
| CN-105899216-A | Pyrrolo [1,2-f ] [1,2,4] triazines useful for the treatment of respiratory syncytial virus infection | 吉利德科学公司 | 2016-08-24 | — | — | CN | disclosed |