Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6040966 | 0.80 | — | — | |
| SCHEMBL152101 | 0.78 | MEN1 (0.46) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6040973 | 0.78 | MEN1 (0.46) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4256819 | 0.73 | MAPT (0.43) | MEN1KMT2AMAPTMMP1MMP3 | |
| SCHEMBL535105 | 0.72 | MEN1 (0.46) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL1276982 | 0.69 | KMT2A (0.50) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL1299737 | 0.69 | MEN1 (0.43) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6040986 | 0.67 | MEN1 (0.37) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL1299741 | 0.67 | FDPS (0.42) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL38651931 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105980381-A | Substituted uracils and use thereof | 拜耳医药股份有限公司 | 2016-09-28 | — | — | CN | disclosed |