Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103412 | 0.92 | P2RX7 (0.38) | PDE4APDE4BPDE4CPDE4DP2RX7 | |
| SCHEMBL28103211 | 0.91 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4DP2RX7 | |
| SCHEMBL28835079 | 0.88 | P2RX7 (0.38) | P2RX7KDM4EPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL28103627 | 0.87 | PDE4A (0.34) | PDE4APDE4BPDE4CPDE4DP2RX7 | |
| SCHEMBL28103422 | 0.81 | RXFP1 (0.36) | PDE4APDE4BPDE4CPDE4DP2RX7 | |
| SCHEMBL173457 | 0.81 | POLB (0.39) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL28103433 | 0.79 | RXFP1 (0.36) | PDE4APDE4BPDE4CPDE4DP2RX7 | |
| SCHEMBL173247 | 0.77 | CRHR1 (0.40) | POLBKMT2AGAAMAPK1SMN1; SMN2 | |
| SCHEMBL170536 | 0.74 | POLB (0.38) | KDM4EPOLBGAAMAPK1TP53 | |
| SCHEMBL28835063 | 0.72 | RXFP1 (0.39) | PDE4APDE4BPDE4CPDE4DP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106417305-A | Fungicidal pyrazoles and their mixtures | 杜邦公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106417305-A | Fungicidal pyrazoles and their mixtures | 杜邦公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-106008299-A | Intermediate for preparing fungicidal pyrazoles | 杜邦公司 | 2016-10-12 | — | — | CN | disclosed |