Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | APC | P25054 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103510 | 0.83 | ALDH1A1 (0.50) | RARGRXRALMNAALDH1A1KDM4E | |
| SCHEMBL28103507 | 0.83 | ALDH1A1 (0.50) | RARGRXRALMNAALDH1A1KDM4E | |
| SCHEMBL28103551 | 0.80 | CCNA2 (0.52) | LMNAALDH1A1KDM4ESMN1; SMN2CXCR5 | |
| SCHEMBL28103577 | 0.80 | CCNA2 (0.52) | LMNAALDH1A1KDM4ESMN1; SMN2CXCR5 | |
| SCHEMBL28103553 | 0.80 | CCNA2 (0.52) | LMNAALDH1A1KDM4ESMN1; SMN2CXCR5 | |
| SCHEMBL28315052 | 0.77 | GRM5 (0.53) | LMNAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28103563 | 0.77 | GRM5 (0.53) | LMNAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28103527 | 0.76 | PHGDH (0.48) | LMNAALDH1A1KDM4ESMN1; SMN2CXCR5 | |
| SCHEMBL28103865 | 0.74 | PTGS2 (0.43) | LMNAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28103548 | 0.71 | GRM5 (0.46) | LMNAALDH1A1KDM4ESMN1; SMN2CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146479-B | A kind of effective compound and the preparation method and application thereof inhibited or kill multiple drug resistant bacteria | 清华大学 | 2019-07-12 | — | — | CN | disclosed |
| CN-106146479-A | A kind of effective suppression or the compound killing multiple drug resistant bacteria and preparation method and application | 清华大学 | 2016-11-23 | — | — | CN | disclosed |