SCHEMBL28103606

SCHEMBL28103606

Oc1ccc(C2(O)C=CC=CC2Br)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28215364 0.78 ESR2 (0.34) ESR1ESR2
SCHEMBL8583721 0.74 ESR2 (0.32) ESR1ESR2
SCHEMBL809093 0.64 ESR1 (0.35) ESR1ESR2
SCHEMBL4114858 0.62
SCHEMBL28717718 0.60
SCHEMBL27947397 0.60
SCHEMBL8763181 0.57 ESR2 (0.42) ESR1ESR2
SCHEMBL4345092 0.56
Hydroquinone SCHEMBL30844901 0.55 ALOX15 (0.80) ESR1ESR2
Hydroquinone SCHEMBL28083633 0.55 ALOX15 (0.80) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104193986-B Curable polyether-ether-ketone and preparation thereof and application 中国科学院上海有机化学研究所 2016-09-14 CN disclosed