SCHEMBL28103641

SCHEMBL28103641

CC(CC(NO)C(=O)O)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 4/20 0.65
NAALAD2 Q9Y3Q0 3/20 0.65
ENPEP Q07075 2/20 0.43
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 1/20 0.41
GABRR1 P24046 2/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 2/20 0.38
ACE P12821 2/20 0.36
MME P08473 2/20 0.36
KDM4E B2RXH2 1/20 0.35
THRB P10828 1/20 0.35
ALOX15 P16050 1/20 0.35
NFKB1 P19838 1/20 0.35
PTGS2 P35354 1/20 0.35
THPO P40225 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4477148 1.00 FOLH1 (0.65) FOLH1NAALAD2ENPEPALDH1A1MEN1
SCHEMBL7450904 0.83 ALDH1A1 (0.61) FOLH1NAALAD2ALDH1A1MEN1LMNA
SCHEMBL818701 0.83 ALDH1A1 (0.61) FOLH1NAALAD2ALDH1A1MEN1LMNA
SCHEMBL818702 0.83 ALDH1A1 (0.61) FOLH1NAALAD2ALDH1A1MEN1LMNA
Ammonia Solution, Strong SCHEMBL28224305 0.81 ALDH1A1 (0.59) FOLH1NAALAD2ALDH1A1MEN1LMNA
SCHEMBL14331634 0.79 FOLH1 (1.00) FOLH1NAALAD2ALDH1A1MEN1LMNA
SCHEMBL27847904 0.79 FOLH1 (0.76) FOLH1NAALAD2ENPEPALDH1A1MEN1
SCHEMBL14331626 0.79 FOLH1 (1.00) FOLH1NAALAD2ALDH1A1MEN1LMNA
SCHEMBL443229 0.76 NAALAD2 (0.56) FOLH1NAALAD2ENPEPGABRR1CYP1A2
SCHEMBL7314519 0.76 NAALAD2 (0.56) FOLH1NAALAD2ENPEPGABRR1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101965397-B Transferases and oxidoreductases, nucleic acids encoding them, and methods for their preparation and use 巴斯夫酶有限责任公司 2016-09-28 CN disclosed