SCHEMBL818702

SCHEMBL818702

CC(C)C[C@H](NO)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
MEN1 O00255 1/20 0.57
LMNA P02545 1/20 0.57
KMT2A Q03164 1/20 0.57
MAPT P10636 1/20 0.53
FOLH1 Q04609 6/20 0.50
LAP3 P28838 3/20 0.47
RNPEP Q9H4A4 1/20 0.46
SLC7A5 Q01650 1/20 0.46
NAALAD2 Q9Y3Q0 2/20 0.45
PLA2G2A P14555 2/20 0.44
PLA2G5 P39877 2/20 0.44
GRN P28799 1/20 0.44
SORT1 Q99523 1/20 0.44
MME P08473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL818701 1.00 ALDH1A1 (0.61) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL7450904 1.00 ALDH1A1 (0.61) ALDH1A1MEN1LMNAKMT2AMAPT
Ammonia Solution, Strong SCHEMBL28224305 0.98 ALDH1A1 (0.59) ALDH1A1MEN1LMNAKMT2AMAPT
Propionaldehyde SCHEMBL27094320 0.88 ALDH1A1 (0.50) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL1963985 0.86 ALDH1A1 (0.48) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL1963988 0.86 ALDH1A1 (0.48) ALDH1A1MEN1LMNAKMT2AMAPT
Serine SCHEMBL6021449 0.84 SLC7A5 (0.53) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL29742735 0.84 ALDH1A1 (0.55) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL4477148 0.83 FOLH1 (0.65) ALDH1A1MEN1LMNAKMT2AMAPT
SCHEMBL28103641 0.83 FOLH1 (0.65) ALDH1A1MEN1LMNAKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025109003-A1 P-CADHERIN LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2025-05-30 WO claimed
WO-2025030099-A1 NON-CANONICAL CELL-PENETRATING PEPTIDES FOR ANTISENSE OLIGOMER DELIVERY SAREPTA THERAPEUTICS, INC. (US) 2025-02-06 WO claimed
EP-4387676-A2 DELIVERY OF ANITSENSE OLIGOMERS BY MIRROR IMAGE PEPTIDES Sarepta Therapeutics, Inc. (US) 2024-06-26 EP claimed
WO-2023034515-A2 DELIVERY OF ANITSENSE OLIGOMERS BY MIRROR IMAGE PEPTIDES SAREPTA THERAPEUTICS, INC. (US) 2023-03-09 WO claimed
US-8415449-B2 Bioresorbable polymers synthesized from monomer analogs of natural metabolites RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-04-09 US claimed
US-20120197001-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-08-02 US claimed
EP-2459617-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES Rutgers, The State University of New Jersey (US) 2012-06-06 EP claimed
US-20110275782-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-11-10 US claimed
EP-2334712-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES Rutgers, The State University of New Jersey (US) 2011-06-22 EP claimed
WO-2011014858-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-02-03 WO claimed
CN-1303991-C Stabilized pharmaceutical preparations of gamma-aminobutyric acid derivative process for preparing the same WARNER LAMBERT CO (US) 2007-03-14 CN claimed
US-20060014159-A1 Methods of determining precise HERG interactions and designing compounds based on said interactions NEURION PHARMACEUTICALS, INC. (US) 2006-01-19 US claimed
EP-1077692-B1 AMINO ACID STABILIZED GABAPENTIN AND PREGABALIN PREPARATIONS AND PROCESS FOR PREPARING THE SAME WARNER LAMBERT CO (US) 2004-07-28 EP claimed
CN-1301155-A Stable pharmaceutical formulation of gamma-aminobutyric acid derivatives and process for preparing the same WARNER LAMBERT CO (US) 2001-06-27 CN claimed
EP-1077692-A1 AMINO ACID STABILIZED GABAPENTIN AND PREGABALIN PREPARATIONS AND PROCESS FOR PREPARING THE SAME Warner-Lambert Company LLC (US) 2001-02-28 EP claimed
EP-1017358-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 2000-07-12 EP claimed
WO-1999059573-A9 STABILIZED PHARMACEUTICAL PREPARATIONS OF GAMMA-AMINOBUTYRIC ACID DERIVATIVES AND PROCESS FOR PREPARING THE SAME WARNER LAMBERT CO (US) 2000-05-04 WO claimed
WO-1999059573-A1 STABILIZED PHARMACEUTICAL PREPARATIONS OF GAMMA-AMINOBUTYRIC ACID DERIVATIVES AND PROCESS FOR PREPARING THE SAME WARNER-LAMBERT COMPANY (US) 1999-11-25 WO claimed
WO-1999015136-A1 REDUCTION OF HAIR GROWTH THE GILLETTE COMPANY (US) 1999-04-01 WO claimed
WO-1995001952-A1 PROCESS FOR SYNTHESIZING O-SUBSTITUTED OXIME COMPOUNDS AND CONVERSION TO THE CORRESPONDING O-SUBSTITUTED HYDROXYLAMINE THE GILLETTE COMPANY (US) 1995-01-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014159-A1 Methods of determining precise HERG interactions and designing compounds based on said interactions KCNN4, KCNC1, HCN4 ALDH1A1 3649/4885MEN1 4279/4885LMNA 2377/4885
US-20110275782-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES BCAT2, WASF2, THEM6 ALDH1A1 2477/4885MEN1 2186/4885LMNA 2479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.