Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28103753

C1CCOC1.O=C(O)C1=CCN=C1

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23829741 0.86
SCHEMBL27625302 0.68 TSHR (0.31)
SCHEMBL3818018 0.66
Tetrahydrofuran SCHEMBL17114599 0.66
Terephthalic Acid SCHEMBL3249925 0.65 TSHR (0.60) PIK3CA
Terephthalic Acid SCHEMBL27839875 0.65 TSHR (0.60) PIK3CA
SCHEMBL1373713 0.64
SCHEMBL20223624 0.64 FFAR1 (0.33)
SCHEMBL25446983 0.64 CA12 (0.38)
Tetrahydrofuran SCHEMBL16166505 0.64 ALDH1A1 (0.61)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106163521-A Potent soluble epoxide hydrolase inhibitors 艾科西斯有限责任公司 2016-11-23 CN disclosed