Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27839875 | 1.00 | TSHR (0.60) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL10970615 | 0.98 | TSHR (0.57) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL29054355 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL1930835 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL28311743 | 0.91 | TSHR (0.64) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL4091430 | 0.90 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL3895453 | 0.90 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL366937 | 0.89 | TSHR (0.48) | TSHRTP53SRD5A2CA1CA2 | |
| Aminobenzoic Acid SCHEMBL53110 | 0.89 | TSHR (0.48) | TSHRTP53SRD5A2CA1CA2 | |
| Benzoic Acid SCHEMBL29256158 | 0.89 | TSHR (0.61) | TSHRTP53SRD5A2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1172825-B1 | MULTILAYER INSULATED WIRE AND TRANSFORMER COMPRISING THE SAME | FURUKAWA ELECTRIC CO LTD (JP) | 2012-08-15 | — | — | EP | claimed |
| US-20070010633-A1 | Toughened polyoxymethylene resin composition | KOLON INDUSTRIES, INC. (KR) | 2007-01-11 | — | — | US | claimed |
| WO-2005116128-A1 | COPOLYETHERESTER COMPOSITION AND MULTILAYER STRUCTURE THEREOF | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-12-08 | — | — | WO | claimed |
| US-20050266190-A1 | Copolyetherester composition and multilayer structure thereof | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-12-01 | — | — | US | claimed |
| US-20050163827-A1 | Transdermal therapeutic delivery system | ZECH HERBERT (AT) | 2005-07-28 | — | — | US | claimed |
| WO-2004058888-A1 | TOUGHENED POLYOXYMETHYLENE RESIN COMPOSITION | KOLON INDUSTRIES, INC. (KR) | 2004-07-15 | — | — | WO | claimed |
| EP-0323612-B1 | INTERLEAFED FIBER-REINFORCED THERMOPLASTIC COMPOSITE | GENERAL ELECTRIC COMPANY (US) | 1993-10-13 | — | — | EP | claimed |
| US-4892774-A | Interleafed fiber-reinforced thermoplastic composite | GENERAL ELECTRIC COMPANY (US) | 1990-01-09 | — | — | US | claimed |
| EP-0323612-A2 | Interleafed fiber-reinforced thermoplastic composite | GENERAL ELECTRIC COMPANY (US) | 1989-07-12 | — | — | EP | claimed |
| EP-0269182-A2 | Light-to-handle paintbrush | AKZO N.V. (NL) | 1988-06-01 | — | — | EP | claimed |
| CN-118103394-A | Composition and use of oligopeptides and method of preparation | 博纳菲德健康有限公司 | 2024-05-28 | — | — | CN | disclosed |
| EP-4041015-B1 | METHODS OF MANUFACTURING ARTICLES UTILIZING FOAM PARTICLES | NIKE INNOVATE CV (US) | 2024-05-22 | — | — | EP | disclosed |
| US-11981788-B2 | Methods of manufacturing articles utilizing foam particles | NIKE, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| US-11969517-B2 | Compositions and methods for macrophage conversion | DREXEL UNIVERSITY (US) | 2024-04-30 | — | — | US | disclosed |
| US-11930882-B2 | Midsole structure of an article of footwear including mesh | NIKE, INC. (US) | 2024-03-19 | — | — | US | disclosed |
| US-4427725-A | Dimensionally-recoverable article | RAYCHEM LIMITED (GB) | 1984-01-24 | — | — | US | disclosed |
| EP-0058091-A2 | Dimensionally-recoverable article | RAYCHEM LIMITED (GB) | 1982-08-18 | — | — | EP | disclosed |
| US-4342806-A | FOR USE AS ENERGY ABSORBER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| EP-0041709-A1 | Energy absorbing belt-like member | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-12-16 | — | — | EP | disclosed |
| US-4094857-A | Copolymerizable phenolic antioxidant | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-13 | — | — | US | disclosed |