Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28104545 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2QRFPRL3MBTL1KMT2AMEN1 | |
| SCHEMBL8611008 | 0.82 | SMN1; SMN2 (0.55) | SMN1; SMN2QRFPRL3MBTL1KMT2AMEN1 | |
| SCHEMBL28104581 | 0.82 | QRFPR (0.45) | SMN1; SMN2QRFPRL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL1710514 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2QRFPRL3MBTL1KMT2AMEN1 | |
| SCHEMBL13577098 | 0.78 | TAAR1 (0.44) | SMN1; SMN2QRFPRL3MBTL1KMT2APTGS1 | |
| SCHEMBL1710758 | 0.75 | TAAR1 (0.48) | QRFPRPPARGPPARATAAR1 | |
| SCHEMBL28543149 | 0.74 | HPGD (0.58) | SMN1; SMN2QRFPRKMT2ARAB9ANPC1 | |
| SCHEMBL28835144 | 0.74 | RAB9A (0.53) | SMN1; SMN2L3MBTL1KMT2ANFE2L2RAB9A | |
| SCHEMBL13577097 | 0.74 | MEN1 (0.43) | QRFPRSLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL28104588 | 0.73 | L3MBTL1 (0.41) | SMN1; SMN2L3MBTL1SLC6A4SLC6A3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102639494-B | Sulphones and preparation and application thereof | 扎夫根公司 | 2016-11-09 | — | — | CN | disclosed |