Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.34 |
| ▸ | GSK3B | P49841 | 5/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23685815 | 0.83 | KDM5A (0.47) | KDM5ANAMPTALOX15MELKFLT4 | |
| SCHEMBL9953033 | 0.83 | KDM5A (0.47) | KDM5ANAMPTALOX15MELKFLT4 | |
| SCHEMBL31361718 | 0.83 | KDM5A (0.47) | KDM5ANAMPTALOX15MELKFLT4 | |
| SCHEMBL27660981 | 0.77 | KDM2B (0.40) | TPMTKDM2BDYRK1AGSK3BCLK2 | |
| SCHEMBL17076683 | 0.75 | KDM5A (0.43) | KDM5AALOX15MELK | |
| SCHEMBL531181 | 0.75 | KDM5A (0.43) | KDM5AALOX15MELK | |
| SCHEMBL216558 | 0.74 | ALOX15 (0.50) | KDM5AALOX15DYRK1AGSK3BCLK2 | |
| SCHEMBL14706020 | 0.73 | ACHE (0.48) | MELKDYRK1AGSK3BCLK2CLK3 | |
| Hydrochloric Acid SCHEMBL15145595 | 0.73 | ALOX15 (0.49) | KDM5AALOX15DYRK1AGSK3BCLK2 | |
| SCHEMBL12093350 | 0.73 | OGA (0.43) | KDM5AALOX15MELKFLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105940004-A | Compounds | 葛兰素史密斯克莱知识产权发展有限公司 | 2016-09-14 | — | — | CN | disclosed |