Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Resveratrol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.79 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.79 |
| ▸ | TTR | P02766 | 5/20 | 0.79 |
| ▸ | LMNA | P02545 | 4/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 4/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.79 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.79 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.79 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.79 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | TP53 | P04637 | 3/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.79 |
| ▸ | HPGD | P15428 | 3/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resveratrol SCHEMBL4898267 | 1.00 | KDM4E (0.79) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL20603099 | 0.89 | KDM4E (0.91) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL20603098 | 0.89 | KDM4E (0.91) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL19425 | 0.89 | PTGS1 (1.00) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL20164915 | 0.89 | PTGS1 (1.00) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL3704258 | 0.89 | PTGS1 (1.00) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL19426 | 0.89 | PTGS1 (1.00) | KDM4EPTGS1TTRLMNAMEN1 | |
| Cis-Resveratrol SCHEMBL1931746 | 0.89 | PTGS1 (1.00) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL17629801 | 0.89 | PTGS1 (1.00) | KDM4EPTGS1TTRLMNAMEN1 | |
| Resveratrol SCHEMBL2300985 | 0.89 | PTGS1 (1.00) | KDM4EPTGS1TTRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117462449-A | Hydrogel loaded with antioxidant nano-drug and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-108014074-B | Preparation method of nano resveratrol suspension and cosmetic composition containing nano resveratrol suspension | 常州药物研究所有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-105709238-B | Embed the peanut protein nano particle and preparation method thereof of resveratrol | 中国农业科学院农产品加工研究所 | 2018-08-17 | — | — | CN | claimed |
| CN-118203559-A | Colon-targeted multilayer nanofiber membrane containing active ingredients and preparation method and application thereof | 华南理工大学 | 2024-06-18 | — | — | CN | disclosed |
| CN-117462449-A | Hydrogel loaded with antioxidant nano-drug and preparation method and application thereof | 江西科技师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-108014074-B | Preparation method of nano resveratrol suspension and cosmetic composition containing nano resveratrol suspension | 常州药物研究所有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-110251421-A | Activating agent-cyclodextrin inclusion compound and its preparation and application containing nucleoprotamine | 上海家化联合股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-109157508-A | A kind of resveratrol nanosuspension and preparation method thereof | 沈阳药科大学 | 2019-01-08 | — | — | CN | disclosed |
| CN-105709238-B | Embed the peanut protein nano particle and preparation method thereof of resveratrol | 中国农业科学院农产品加工研究所 | 2018-08-17 | — | — | CN | disclosed |
| CN-104801247-B | A kind of control release type yeast cells microcapsule product and preparation method thereof | 湖南农业大学 | 2017-06-16 | — | — | CN | disclosed |
| CN-106176627-A | Method for preparing polydatin resveratrol and emodin | 湖南鑫利生物科技有限公司 | 2016-12-07 | — | — | CN | disclosed |