Resveratrol

Resveratrol

SCHEMBL4898267

CCO.Oc1ccc(/C=C/c2cc(O)cc(O)c2)cc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Resveratrol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP8 known ✓ P22894 1/20 0.53
▸ KDM4E B2RXH2 5/20 0.79
▸ PTGS1 P23219 5/20 0.79
▸ TTR P02766 5/20 0.79
▸ LMNA P02545 4/20 0.79
▸ MEN1 O00255 4/20 0.79
▸ MAPT P10636 4/20 0.79
▸ KMT2A Q03164 4/20 0.79
▸ CYP1A1 P04798 4/20 0.79
▸ PTGS2 P35354 4/20 0.79
▸ CYP1B1 Q16678 4/20 0.79
▸ ALOX5 P09917 4/20 0.79
▸ ALDH1A1 P00352 3/20 0.79
▸ TP53 P04637 3/20 0.79
▸ CYP1A2 P05177 3/20 0.79
▸ CYP3A4 P08684 3/20 0.79
▸ CYP2C9 P11712 3/20 0.79
▸ HPGD P15428 3/20 0.79
▸ SMN1; SMN2 Q16637 3/20 0.79
▸ HIF1A Q16665 3/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resveratrol SCHEMBL28105805 1.00 KDM4E (0.79) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL20603099 0.89 KDM4E (0.91) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL20603098 0.89 KDM4E (0.91) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL19425 0.89 PTGS1 (1.00) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL20164915 0.89 PTGS1 (1.00) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL3704258 0.89 PTGS1 (1.00) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL19426 0.89 PTGS1 (1.00) KDM4EPTGS1TTRLMNAMEN1
Cis-Resveratrol SCHEMBL1931746 0.89 PTGS1 (1.00) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL17629801 0.89 PTGS1 (1.00) KDM4EPTGS1TTRLMNAMEN1
Resveratrol SCHEMBL2300985 0.89 PTGS1 (1.00) KDM4EPTGS1TTRLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115998712-B Resveratrol nanosphere material and preparation method and application thereof 吉林大学 2024-06-21 — — CN claimed
CN-118058320-A Preparation method of spicy moon cake combined with spice essential oil microcapsules 郑州雪麦龙食品香料有限公司 2024-05-24 — — CN claimed
CN-117678750-A Preparation method of resveratrol-loaded egg white protein nano-particles and application of resveratrol-loaded egg white protein nano-particles in antioxidation of emulsion interface 华南农业大学 2024-03-12 — — CN claimed
CN-115998712-A Resveratrol nanosphere material and preparation method and application thereof 吉林大学 2023-04-25 — — CN claimed
CN-110742281-B Resveratrol-dietary fiber solid dispersion and preparation method thereof 江南大学 2023-04-25 — — CN claimed
CN-115737887-A Skin wound dressing and preparation method thereof 河北大学 2023-03-07 — — CN claimed
CN-115252538-A Preparation method of photo-thermal controlled drug release poly-dopamine iron drug-loaded nanoparticle hydrogel 西北大学 2022-11-01 — — CN claimed
CN-111150050-B Preparation method of resveratrol microcapsule 浙江工商大学 2022-09-30 — — CN claimed
CN-115073901-A PLA material with antibacterial function and processing method thereof 东莞市创之润新材料有限公司 2022-09-20 — — CN claimed
CN-115053927-A Preparation method of functional two-phase conversion network structure emulsion 长春职业技术学院 2022-09-16 — — CN claimed
CN-110742281-A Resveratrol-dietary fiber solid dispersion and preparation method thereof 江南大学 2020-02-04 — — CN claimed
CN-110663385-A Novel application of novel compound in improving potassium ion stress resistance of Malus hupehensis Rehd 青岛农业大学 2020-01-10 — — CN claimed
CN-106620711-B A kind of composition and preparation method thereof containing resveratrol 中国科学院大连化学物理研究所 2019-06-25 — — CN claimed
CN-109157508-A A kind of resveratrol nanosuspension and preparation method thereof 沈阳药科大学 2019-01-08 — — CN claimed
CN-106176627-B Method for preparing polydatin resveratrol and emodin 湖南鑫利生物科技有限公司 2018-10-30 — — CN claimed
CN-105709238-B Embed the peanut protein nano particle and preparation method thereof of resveratrol 中国农业科学院农产品加工研究所 2018-08-17 — — CN claimed
CN-108014074-A The preparation method of nanometer resveratrol suspension and the cosmetic composition for including nanometer resveratrol suspension 常州药物研究所有限公司 2018-05-11 — — CN claimed
CN-106620711-A Resveratrol-containing composition and preparation method thereof 中国科学院大连化学物理研究所 2017-05-10 — — CN claimed
CN-106176627-A Method for preparing polydatin resveratrol and emodin 湖南鑫利生物科技有限公司 2016-12-07 — — CN claimed
CN-105055375-A Amycin and resveratrol co-delivery nano drug delivery system with anti-multi-drug-resistance effect FOURTH MILITARY MEDICAL UNIV 2015-11-18 — — CN claimed
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