Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PMM2 | O15305 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MPI | P34949 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767507 | 0.79 | ALDH1A1 (0.48) | KDM4EHSD17B10ALDH1A1HPGDPOLB | |
| SCHEMBL18502949 | 0.77 | SLC6A2 (0.46) | MAPK1MAP4K1PIM1 | |
| SCHEMBL20038317 | 0.75 | RECQL (0.37) | MAP4K1PIM1ALOX5ADRB1TLR8 | |
| SCHEMBL5797268 | 0.74 | ADRB1 (0.59) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL31518606 | 0.74 | ADRB1 (0.59) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| Hydrochloric Acid SCHEMBL7868157 | 0.73 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDSORD | |
| Hydrochloric Acid SCHEMBL5375047 | 0.73 | KDM4E (0.59) | KDM4EHSD17B10ALDH1A1HPGDSORD | |
| SCHEMBL29991218 | 0.73 | HRH3 (0.36) | MAP4K1PIM1TLR8TLR7HRH3 | |
| SCHEMBL255543 | 0.72 | SLC6A2 (0.43) | MAP4K1PIM1ADRB1 | |
| SCHEMBL9199798 | 0.71 | SLC6A2 (0.36) | KDM4EALDH1A1MAP4K1PIM1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470924-B | Imidazopyrazines derivant as TNF active regulator | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |