Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.95 |
| ▸ | MEN1 | O00255 | 1/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.95 |
| ▸ | POLB | P06746 | 1/20 | 0.95 |
| ▸ | GAA | P10253 | 1/20 | 0.95 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.95 |
| ▸ | HPGD | P15428 | 1/20 | 0.95 |
| ▸ | TSHR | P16473 | 1/20 | 0.95 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.95 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.95 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.95 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | DHFR | P00374 | 7/20 | 0.64 |
| ▸ | GART | P22102 | 2/20 | 0.64 |
| ▸ | ATIC | P31939 | 2/20 | 0.64 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.55 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Folic Acid SCHEMBL29357550 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29349485 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29441959 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL403054 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29388311 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL248712 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL16492117 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL332170 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL3877 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB | |
| Folic Acid SCHEMBL29624885 | 0.97 | TYMS (1.00) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116492286-A | Periodontal microneedle carrying near infrared responsive composite bilirubin nano particles and preparation method thereof | 重庆医科大学附属口腔医院 | 2023-07-28 | — | — | CN | disclosed |
| CN-110501208-B | Folic acid functionalized streptavidin modified magnetic nanoparticle, preparation method and application thereof | 国家纳米科学中心 | 2023-06-27 | — | — | CN | disclosed |
| CN-113975388-A | Polydopamine modified black phosphorus nanocomposite and preparation method thereof | 深圳市人民医院 | 2022-01-28 | — | — | CN | disclosed |
| CN-112823810-A | Active targeting gold nanoprobe based on folate receptor and preparation method thereof | 江苏师范大学 | 2021-05-21 | — | — | CN | disclosed |
| CN-110501208-A | Magnetic nanoparticle, preparation method and the application of the Streptavidin modification of folic acid functionalization | NAT CT NANOSCIENCE & TECHNOLOGY CHINA | 2019-11-26 | — | — | CN | disclosed |
| CN-106083898-B | A kind of tumor-targeting gambogic acid compounds and its preparation method and application | 彭咏波 | 2019-02-12 | — | — | CN | disclosed |
| CN-104892949-B | A kind of glutathione/pH double stimuli responsive ionomer type polymer nano hydrogels and its preparation method and application | 复旦大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-106083898-A | A kind of tumor-targeting gambogic acid compounds and its production and use | 彭咏波 | 2016-11-09 | — | — | CN | disclosed |