Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 13/20 | 0.70 |
| ▸ | NPC1 | O15118 | 12/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13912 | 0.86 | KMT2A (0.75) | RAB9ANPC1GAANPSR1MEN1 | |
| SCHEMBL1430921 | 0.85 | RAB9A (0.64) | RAB9ANPC1GAANPSR1MEN1 | |
| SCHEMBL19988167 | 0.84 | CA12 (0.65) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL1852166 | 0.84 | MAPT (0.66) | RAB9ANPC1GAANPSR1MEN1 | |
| SCHEMBL14365697 | 0.83 | RAB9A (0.62) | RAB9ANPC1GAANPSR1MEN1 | |
| SCHEMBL4972639 | 0.82 | CYP1A2 (0.72) | RAB9ANPC1GAANPSR1MEN1 | |
| SCHEMBL4743849 | 0.82 | MEN1 (0.72) | RAB9ANPC1GAANPSR1MEN1 | |
| SCHEMBL5740173 | 0.82 | MAPT (0.77) | RAB9ANPC1GAANPSR1MEN1 | |
| SCHEMBL7454467 | 0.82 | KMT2A (0.72) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12313402 | 0.82 | POLB (0.62) | RAB9ANPC1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341141-A | Camptothecin derivatives having a disulfide moiety and a piperazine moiety | 太阳医药高级研究有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-106103445-B | The therapeutical uses of pyrazolo [1,5-A] pyrimidine -5,7- diamine compound and they as CDK inhibitor | 癌症研究技术有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-106103445-A | Pyrazolo [1,5 A] pyrimidine 5,7 diamine compound and their therapeutic use as CDK inhibitor | 癌症研究技术有限公司 | 2016-11-09 | — | — | CN | disclosed |