SCHEMBL4743849

SCHEMBL4743849

CN1CCN(c2ccc(NC(=O)NN)cc2)CC1

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.72
KMT2A Q03164 2/20 0.72
RAB9A P51151 11/20 0.61
NPC1 O15118 10/20 0.61
SMN1; SMN2 Q16637 2/20 0.57
GAA P10253 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
JAK3 P52333 1/20 0.56
TSHR P16473 1/20 0.56
KDM1A O60341 3/20 0.54
MAOA P21397 3/20 0.54
MAOB P27338 3/20 0.54
KDM1B Q8NB78 3/20 0.54
RCOR1 Q9UKL0 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14365697 0.86 RAB9A (0.62) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL20639990 0.84 KMT2A (0.68) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL1430921 0.84 RAB9A (0.64) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL5003684 0.84 MAPT (0.72) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL3568215 0.84 KMT2A (1.00) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL28152842 0.83 MEN1 (0.66) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL13912 0.82 KMT2A (0.75) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL28106923 0.82 RAB9A (0.70) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL14850178 0.82 MEN1 (0.60) MEN1KMT2ARAB9ANPC1SMN1; SMN2
SCHEMBL12264104 0.81 MEN1 (0.62) MEN1KMT2ARAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-07-31 US disclosed
US-12269800-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2025-04-08 US disclosed
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2025-02-13 US disclosed
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2024-07-25 US disclosed
US-11999694-B2 Delivery of therapeutic alkaloid compounds SENSORIUM THERAPEUTICS, INC. (US) 2024-06-04 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. 2023-05-25 US disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
WO-2023076586-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS SENSORIUM THERAPEUTICS, INC. (US) 2023-05-04 WO disclosed
WO-2008103353-A1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY SYNTA PHARMACEUTICALS CORP. (US) 2008-08-28 WO disclosed
WO-2008103353-A1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY SYNTA PHARMACEUTICALS CORP. (US) 2008-08-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051277-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885RAB9A 571/4885
US-20250243161-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885RAB9A 571/4885
US-20230159455-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885RAB9A 571/4885
US-20240246910-A1 DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885RAB9A 571/4885
US-12269800-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885RAB9A 571/4885
US-11999694-B2 Delivery of therapeutic alkaloid compounds PNMT, HNMT, NNMT MEN1 163/4885KMT2A 2128/4885RAB9A 571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.