Ethylene

Ethylene

SCHEMBL28106925

C=C.COc1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 1/20 0.44
TSHR P16473 2/20 0.43
HSD17B10 Q99714 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HPGD P15428 2/20 0.43
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MEN1 O00255 2/20 0.42
CYP2C9 P11712 1/20 0.42
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP2C19 P33261 1/20 0.40
TPMT P51580 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54507 0.95 KMT2A (0.47) KMT2AALDH1A1KDM4EGAATSHR
Benzene SCHEMBL29202175 0.90 KMT2A (0.50) KMT2AALDH1A1KDM4EGAATSHR
Butadiene SCHEMBL3372131 0.88 ALDH1A1 (0.44) KMT2AALDH1A1KDM4EGAATSHR
SCHEMBL10510118 0.80 MAPT (0.50) KMT2AALDH1A1KDM4ETSHRHSD17B10
SCHEMBL1387190 0.79 ALDH1A1 (0.44) KMT2AALDH1A1KDM4EGAAHSD17B10
SCHEMBL23409566 0.78 KMT2A (0.45) KMT2AALDH1A1KDM4EGAATSHR
SCHEMBL19088270 0.78 KMT2A (0.41) KMT2AALDH1A1KDM4EGAATSHR
SCHEMBL9332735 0.78 TPMT (0.58) KMT2AALDH1A1KDM4EGAATSHR
SCHEMBL6079187 0.78 GAA (0.43) KMT2AALDH1A1KDM4EGAATSHR
SCHEMBL2415199 0.78 CA2 (0.46) KMT2AALDH1A1KDM4EGAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104093560-B Thin-film laminate 日本曹达株式会社 2016-10-26 CN disclosed