Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18851069 | 0.89 | NR1H2 (0.40) | NR1H2MEN1KMT2ANR1H3CA12 | |
| SCHEMBL17022491 | 0.84 | NR1H2 (0.40) | NR1H2MEN1KMT2ACCR9NR1H3 | |
| SCHEMBL13515283 | 0.84 | AKR1C3 (0.40) | NR1H2MEN1KMT2ACCR9NR1H3 | |
| SCHEMBL17433471 | 0.83 | USP30 (0.44) | NR1H2CCR9NR1H3CA12CA9 | |
| SCHEMBL24077249 | 0.82 | NR1H2 (0.46) | NR1H2CCR9NR1H3ALDH1A1STS | |
| SCHEMBL19013262 | 0.82 | CCR9 (0.51) | NR1H2MEN1KMT2ACCR9NR1H3 | |
| SCHEMBL7913537 | 0.81 | NR1H2 (0.56) | NR1H2NR1H3CA12CA9 | |
| SCHEMBL18990058 | 0.81 | NR1H2 (0.40) | NR1H2MEN1KMT2ACCR9NR1H3 | |
| SCHEMBL18989952 | 0.81 | NR1H2 (0.41) | NR1H2MEN1KMT2ACCR9NR1H3 | |
| SCHEMBL1605189 | 0.81 | NR1H2 (0.38) | NR1H2MEN1KMT2ACCR9NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193725-B | Organic compound | 诺华股份有限公司 | 2016-11-16 | — | — | CN | disclosed |