Methyl Isobutyl Ketone

Methyl Isobutyl Ketone

SCHEMBL28107139

CC(=O)CC(C)C.CC(C)=O.CCC(C)=O.CCCC(C)=O

nearest known ligand 0.61

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Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
TDP1 Q9NUW8 2/20 0.61
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
CA2 P00918 1/20 0.34
HDAC3 O15379 4/20 0.33
HDAC1 Q13547 4/20 0.33
HDAC2 Q92769 4/20 0.33
HDAC8 Q9BY41 4/20 0.33
FFAR3 O14843 3/20 0.33
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.32
SLC15A2 Q16348 1/20 0.32
KISS1R Q969F8 2/20 0.31
FFAR1 O14842 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Isobutyl Ketone SCHEMBL9817215 0.93 ALDH1A1 (0.70) ALDH1A1TDP1CES2CES1CA2
Methyl Isobutyl Ketone SCHEMBL2240499 0.89 ALDH1A1 (0.78) ALDH1A1TDP1CA2FFAR3LMNA
Methyl Isobutyl Ketone SCHEMBL306141 0.86 ALDH1A1 (0.82) ALDH1A1TDP1CA2FFAR3
Methyl Isobutyl Ketone SCHEMBL28071916 0.86 ALDH1A1 (0.54) ALDH1A1TDP1CES2CES1TSHR
Methyl Isobutyl Ketone SCHEMBL7057338 0.85 ALDH1A1 (0.58) ALDH1A1TDP1CES2CES1CA2
SCHEMBL28649278 0.82 ALDH1A1 (0.52) ALDH1A1TDP1CES2CES1CA2
Methyl Isobutyl Ketone SCHEMBL22321104 0.82 ALDH1A1 (0.67) ALDH1A1TDP1CES2CES1CA2
Methyl Isobutyl Ketone SCHEMBL28106970 0.81 ALDH1A1 (0.74) ALDH1A1TDP1CA2FFAR3
Methyl Isobutyl Ketone SCHEMBL9056069 0.81 ALDH1A1 (0.82) ALDH1A1TDP1CA2FFAR1
Butanone SCHEMBL3197137 0.81 ALDH1A1 (0.67) ALDH1A1TDP1CES2CES1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106029836-A Liquid crystal alignment composition, liquid crystal alignment film and liquid crystal display element 罗利克有限公司 2016-10-12 CN disclosed