Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16410354 | 0.83 | MTNR1A (0.39) | MTNR1AMTNR1BTDP1DDB1CRBN | |
| SCHEMBL2556108 | 0.78 | MTNR1A (0.42) | MTNR1AMTNR1BL3MBTL1SLC7A5KMT2A | |
| SCHEMBL17772631 | 0.78 | MTNR1A (0.36) | MTNR1AMTNR1BGRM6SLC7A5AAK1 | |
| SCHEMBL2432439 | 0.75 | ALDH1A1 (0.45) | MTNR1AMTNR1BMAPTTDP1SLC7A5 | |
| SCHEMBL28460387 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BLMNAL3MBTL1 | |
| SCHEMBL30038691 | 0.74 | MTNR1A (0.44) | MTNR1AMTNR1BLMNAL3MBTL1 | |
| SCHEMBL17772621 | 0.73 | MTNR1A (0.33) | MTNR1AMTNR1BGRM6 | |
| SCHEMBL13136744 | 0.72 | MAPK1 (0.45) | MTNR1AMTNR1BLMNAGAAKMT2A | |
| SCHEMBL16410214 | 0.72 | MTNR1A (0.44) | MTNR1AMTNR1BL3MBTL1SLC7A5 | |
| SCHEMBL18086521 | 0.72 | MTNR1A (0.44) | MTNR1AMTNR1BMAPTTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132406-A | β substituted γ aminoacid and analog as chemotherapeutics | 夸德里加生物科学公司 | 2016-11-16 | — | — | CN | disclosed |