SCHEMBL28107377

SCHEMBL28107377

CCCCCCCCCCn1ccc2ccccc21

nearest known ligand 0.82

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 4/20 0.82
CCND1 P24385 4/20 0.82
HTR2A P28223 1/20 0.57
HTR2C P28335 1/20 0.57
LMNA P02545 1/20 0.50
P2RX7 Q99572 1/20 0.50
TLR8 Q9NR97 1/20 0.50
TLR7 Q9NYK1 1/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
ABCB1 P08183 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4976386 1.00 CDK4 (0.82) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL29767815 1.00 CDK4 (0.82) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL19748097 1.00 CDK4 (0.82) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL31454116 1.00 CDK4 (0.82) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL30376 1.00 CDK4 (0.82) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL4554026 0.98 CDK4 (0.81) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL30495581 0.98 CDK4 (0.81) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL464099 0.93 CDK4 (0.78) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL29374771 0.93 CDK4 (0.78) CDK4CCND1HTR2AHTR2CLMNA
SCHEMBL15924634 0.91 CDK4 (0.68) CDK4CCND1HTR2AHTR2CTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106117113-A Polysubstituted carbazole, derivant and synthetic method thereof 湘潭大学 2016-11-16 CN claimed
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES PASCAL BIOSCIENCES INC (CA) 2023-08-31 US disclosed
CN-106117113-B Polysubstituted carbazole, derivative and its synthetic method 湘潭大学 2019-08-16 CN disclosed
CN-106117113-A Polysubstituted carbazole, derivant and synthetic method thereof 湘潭大学 2016-11-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270763-A1 METHOD OF TREATING CORONOVIRUS INFECTIONS WITH CANNABINOIDS AND DERIVATIVES CNR1, CNR2, SARS1 CDK4 2566/4885CCND1 4193/4885HTR2A 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.