Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.81 |
| ▸ | CCND1 | P24385 | 4/20 | 0.81 |
| ▸ | HTR2A | P28223 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30495581 | 1.00 | CDK4 (0.81) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL30376 | 0.98 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL29767815 | 0.98 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL19748097 | 0.98 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL31454116 | 0.98 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL28107377 | 0.98 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL4976386 | 0.98 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL29374771 | 0.94 | CDK4 (0.78) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL464099 | 0.94 | CDK4 (0.78) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL15924634 | 0.89 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118546235-A | Synthetic cannabinoid UR-144 antigen and preparation method thereof | 浙江隆基生物技术有限公司 | 2024-08-27 | — | — | CN | claimed |
| CN-117815105-A | Cosmetic containing peptide composition and preparation method thereof | 刘加英 | 2024-04-05 | — | — | CN | claimed |
| CN-110183373-B | Optically active 1-aryl indole derivative and preparation method and application thereof | 浙江大学 | 2020-10-13 | — | — | CN | claimed |
| EP-1204650-B1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | CANCER RES VENTURES LTD (GB) | 2006-04-19 | — | — | EP | claimed |
| US-6858633-B1 | Substituted 2-arylbenzazole compounds and their use as antitumour agents | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2005-02-22 | — | — | US | claimed |
| EP-1204650-A1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | Cancer Research Ventures Limited (GB) | 2002-05-15 | — | — | EP | claimed |
| WO-2001014354-A1 | SUBSTITUTED 2-ARYLBENZAZOLE COMPOUNDS AND THEIR USE AS ANTITUMOUR AGENTS | CANCER RESEARCH VENTURES LIMITED (GB) | 2001-03-01 | — | — | WO | claimed |
| EP-0734384-B1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | LUNDBECK & CO AS H (DK) | 2000-08-09 | — | — | EP | claimed |
| EP-0939077-A2 | 3-Substituted 1-arylindole compounds as 5-HT2 antagonists | H. LUNDBECK A/S (DK) | 1999-09-01 | — | — | EP | claimed |
| US-5789404-A | CENTRAL NERVOUS SYSTEM DISORDERS AND ANTISEROTONIN AGENTS | H. LUNDBECK A/S (DK) | 1998-08-04 | — | — | US | claimed |
| EP-0734384-A1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1996-10-02 | — | — | EP | claimed |
| WO-1995016684-A1 | 3-SUBSTITUTED 1-ARYLINDOLE COMPOUNDS | H. LUNDBECK A/S (DK) | 1995-06-22 | — | — | WO | claimed |
| EP-0618799-A1 | USE OF ARYLINDOLE DERIVATIVES FOR THE TREATMENT OF PSYCHOSES | H. LUNDBECK A/S (DK) | 1994-10-12 | — | — | EP | claimed |
| WO-1993012790-A1 | USE OF ARYLINDOLE DERIVATIVES FOR THE TREATMENT OF PSYCHOSES | H. LUNDBECK A/S (DK) | 1993-07-08 | — | — | WO | claimed |
| JP-54076577-A | — | — | None | — | — | JP | disclosed |
| JP-54076576-A | — | — | None | — | — | JP | disclosed |
| JP-63079873-A | — | — | None | — | — | JP | disclosed |
| JP-S5476576-A | PREPARATION OF 1-ACYL-2,3-DIACYLOXYINDOLINE | MITSUI PETROCHEM IND LTD | 1979-06-19 | — | — | JP | disclosed |
| JP-S5476577-A | 1-ACYLINDOLINE DERIVATIVE | MITSUI PETROCHEM IND LTD | 1979-06-19 | — | — | JP | disclosed |
| US-4046752-A | Process for preparing an azo compound from a 2-aminothiazole diazo component | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |