Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.78 |
| ▸ | CCND1 | P24385 | 4/20 | 0.78 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.52 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29374771 | 1.00 | CDK4 (0.78) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL4554026 | 0.94 | CDK4 (0.81) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL30495581 | 0.94 | CDK4 (0.81) | CDK4CCND1HTR2AHTR2CLMNA | |
| Biphenyl SCHEMBL28740978 | 0.93 | CDK4 (0.68) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL19748097 | 0.93 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL30376 | 0.93 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL29767815 | 0.93 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL31454116 | 0.93 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL4976386 | 0.93 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA | |
| SCHEMBL28107377 | 0.93 | CDK4 (0.82) | CDK4CCND1HTR2AHTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028655-B | 2-trifluoromethyl-3-iodo-indole compound and preparation method thereof | 上海大学 | 2024-01-16 | — | — | CN | claimed |
| CN-115028655-A | 2-trifluoromethyl-3-iodine-indole compound and preparation method thereof | 上海大学 | 2022-09-09 | — | — | CN | claimed |
| CN-104788328-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2015-07-22 | — | — | CN | claimed |
| CN-103641765-A | Modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2014-03-19 | — | — | CN | claimed |
| US-20070207284-A1 | Barrier article and method | MCCLINTIC SHAWN A | 2007-09-06 | — | — | US | claimed |
| US-6513439-B2 | Apparatus for marking a target | DON-B CORPORATION | 2003-02-04 | — | — | US | claimed |
| CN-115028655-B | 2-trifluoromethyl-3-iodo-indole compound and preparation method thereof | 上海大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-117024325-A | Double-indole-containing quaternary ammonium salt, preparation method and application of double-indole-containing quaternary ammonium salt in catalytic preparation of five-membered ring carbonate | 浙江众立合成材料科技股份有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115232051-B | Method for preparing N-substituted indole derivative | 华中科技大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-116332979-A | 3-indole-o-carborane methanol derivative and green synthesis method thereof | 西南科技大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-115232051-A | Method for preparing N-substituted indole derivative | 华中科技大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115028655-A | 2-trifluoromethyl-3-iodine-indole compound and preparation method thereof | 上海大学 | 2022-09-09 | — | — | CN | disclosed |
| US-11319540-B2 | HIF 1-alpha antisense oligonucleotides | OLIPASS CORPORATION (KR) | 2022-05-03 | — | — | US | disclosed |
| EP-0574618-A1 | Thermally transferable fluorescent compounds | AGFA-GEVAERT N.V. (BE) | 1993-12-22 | — | — | EP | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| CN-1078469-A | Substituted indole, the assorted indoles of ammonia and tetrahydro-1 H-pyrrolo be [2,3-c] pyridin-7-one derivatives also | SYTEX A INC (US) | 1993-11-17 | — | — | CN | disclosed |
| EP-0471609-A1 | Benzofuran Derivatives, Benzothiophenes, Indoles or Indolizines, Process for Production and Compositions containing them | SANOFI (FR) | 1992-02-19 | — | — | EP | disclosed |
| US-4525588-A | FOR HEAT AND PRESSURE SENSITIVE RECORDING MATERIALS | CIBA GEIGY CORPORATION (US) | 1985-06-25 | — | — | US | disclosed |
| US-4138396-A | Pyridyl-azo-indolyl cationic dyes | CIBA-GEIGY CORPORATION (US) | 1979-02-06 | — | — | US | disclosed |
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319540-B2 | HIF 1-alpha antisense oligonucleotides | HIF1A, HIF1AN, UPF1 | CDK4 2157/4885CCND1 2310/4885HTR2A 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.