Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 7/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467931 | 0.88 | PTGDR2 (0.38) | PTGDR2LMNAKLKB1KLK1TP53 | |
| SCHEMBL1833832 | 0.86 | KLKB1 (0.35) | PTGDR2LMNAKLKB1KLK1 | |
| SCHEMBL2161213 | 0.81 | KLKB1 (0.36) | PTGDR2KLKB1KLK1 | |
| SCHEMBL1836900 | 0.79 | SKP2 (0.35) | LMNAKLKB1KLK1MAPTALDH1A1 | |
| SCHEMBL1830791 | 0.79 | KLKB1 (0.35) | PTGDR2KLKB1KLK1 | |
| SCHEMBL2161215 | 0.78 | KLKB1 (0.39) | LMNAKLKB1KLK1 | |
| SCHEMBL1831113 | 0.77 | LMNA (0.35) | LMNAKLKB1KLK1MAPTCYP1A2 | |
| SCHEMBL12469860 | 0.75 | KLKB1 (0.33) | KLKB1KLK1 | |
| SCHEMBL1836652 | 0.74 | KLKB1 (0.35) | PTGDR2KLKB1KLK1 | |
| SCHEMBL2161844 | 0.71 | MAPT (0.37) | PTGDR2LMNAKLKB1KLK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012442-A2 | INSECTICIDAL BENZENEDICARBOXAMIDE DERIVATIVE | BAYER CROPSCIENCE AG (DE) | 2010-02-04 | — | — | WO | disclosed |