Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 10/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.33 |
| ▸ | KLK1 | P06870 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1830791 | 0.82 | KLKB1 (0.35) | KLKB1GRIA2KLK1 | |
| SCHEMBL12467931 | 0.80 | PTGDR2 (0.38) | KLKB1KLK1 | |
| SCHEMBL2810810 | 0.75 | PTGDR2 (0.43) | KLKB1KLK1 | |
| SCHEMBL1836900 | 0.74 | SKP2 (0.35) | KLKB1GRIA2KLK1GRM2 | |
| SCHEMBL2161213 | 0.74 | KLKB1 (0.36) | KLKB1GRIA2KLK1 | |
| SCHEMBL1833832 | 0.72 | KLKB1 (0.35) | KLKB1GRIA2KLK1 | |
| SCHEMBL22115129 | 0.69 | ABL1 (0.38) | ABL1 | |
| SCHEMBL23093089 | 0.68 | SKP2 (0.42) | — | |
| SCHEMBL2161475 | 0.66 | KLKB1 (0.39) | KLKB1GRIA2KLK1GRM2 | |
| SCHEMBL1832743 | 0.66 | LMNA (0.37) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184188-A1 | Insecticidal Benzenedicarboxamide Derivative | DDT, BRD9, BCL2A1 | KLKB1 4858/4885GRIA2 3485/4885KLK1 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.