Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422554 | 0.77 | HDAC8 (0.36) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL3902556 | 0.77 | HDAC8 (0.36) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL2811905 | 0.74 | ALDH1A1 (0.36) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL689115 | 0.71 | PTPN1 (0.41) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL3841101 | 0.71 | HDAC8 (0.34) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL30262836 | 0.71 | HDAC8 (0.34) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL2806303 | 0.71 | CA12 (0.35) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL16182687 | 0.71 | HDAC8 (0.34) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL9861993 | 0.71 | TRPV4 (0.34) | HDAC8CA12CA1CA2CA9 | |
| SCHEMBL9793597 | 0.71 | AR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | HDAC8 513/4885CA12 2006/4885CA1 1402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.