Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.93 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.60 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Nicotinate SCHEMBL28109412 | 0.98 | ALDH1A1 (0.96) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL820747 | 0.96 | ALDH1A1 (1.00) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL24566 | 0.96 | ALDH1A1 (1.00) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL29386553 | 0.96 | ALDH1A1 (1.00) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL28247726 | 0.95 | ALDH1A1 (0.89) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL11491005 | 0.94 | ALDH1A1 (0.96) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL29527047 | 0.94 | ALDH1A1 (0.96) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL28370871 | 0.94 | ALDH1A1 (0.96) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL30791985 | 0.94 | ALDH1A1 (0.96) | ALDH1A1KMT2AAPPGAAHCAR3 | |
| Methyl Nicotinate SCHEMBL30779127 | 0.94 | ALDH1A1 (0.96) | ALDH1A1KMT2AAPPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884047-B | Intermediates for the synthesis of aryl or heteroaryl substituted 5-hydroxy-1, 7-naphthyridine compounds and methods for their preparation | 沈阳三生制药有限责任公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-106146491-B | The naphthyridine compounds of 5 hydroxyl 1,7, its preparation method and its pharmaceutical applications being optionally substituted aryl or heteroaryl | 沈阳三生制药有限责任公司 | 2017-12-12 | — | — | CN | disclosed |
| CN-106146491-A | 5-hydroxyl-1,7-naphthyridine compounds, its preparation method and the pharmaceutical applications thereof being optionally substituted aryl or heteroaryl | 沈阳三生制药有限责任公司 | 2016-11-23 | — | — | CN | disclosed |