Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766673 | 0.80 | MEN1 (0.44) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL1285155 | 0.77 | MEN1 (0.58) | MEN1KMT2AALDH1A1POLBHPGD | |
| SCHEMBL20343653 | 0.77 | KMT2A (0.41) | MEN1KMT2AALDH1A1HDAC7HDAC8 | |
| SCHEMBL165731 | 0.76 | — | — | |
| SCHEMBL18628621 | 0.76 | MEN1 (0.56) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL21227418 | 0.76 | ALDH1A1 (0.59) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL12799428 | 0.75 | MEN1 (0.78) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL8851229 | 0.74 | MEN1 (0.54) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL25853656 | 0.74 | MEN1 (0.54) | MEN1KMT2AMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL11330562 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458957-A | Novel cell-permeable succinate compounds | 纽维制药有限公司 | 2017-02-22 | — | — | CN | disclosed |