Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20343653 | 0.91 | KMT2A (0.41) | MEN1KMT2AHDAC8HDAC6HDAC7 | |
| SCHEMBL28122056 | 0.90 | MEN1 (0.42) | MEN1KMT2AFAAH | |
| SCHEMBL19662464 | 0.84 | CASP2 (0.45) | HDAC8HDAC6HDAC1HDAC2CYP3A4 | |
| SCHEMBL17624747 | 0.81 | KMT2A (0.48) | MEN1KMT2ACYP2C9TSHRPSMB5 | |
| SCHEMBL28108993 | 0.80 | MEN1 (0.54) | MEN1KMT2AHDAC8HDAC6HDAC7 | |
| SCHEMBL18908557 | 0.80 | MEN1 (0.43) | MEN1KMT2AHDAC8HDAC6HDAC7 | |
| SCHEMBL25963585 | 0.80 | MEN1 (0.43) | MEN1KMT2AHDAC8HDAC6HDAC7 | |
| SCHEMBL8515067 | 0.79 | TSHR (0.55) | MEN1KMT2ATDP1TSHRCYP3A4 | |
| SCHEMBL14397158 | 0.79 | PAOX (0.39) | HDAC8HDAC6HDAC7HDAC9HDAC5 | |
| SCHEMBL25776053 | 0.78 | MEN1 (0.41) | MEN1KMT2AHDAC8HDAC6HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130342-A1 | TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS | UNIQUEST PTY LIMITED (AU) | 2024-06-27 | — | — | WO | disclosed |
| EP-3402785-B1 | 3-(CARBOXYMETHYL)-8-AMINO-2-OXO-1,3-DIAZA-SPIRO-[4.5]-DECANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |