Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 4/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700642 | 0.96 | CYP1A2 (0.42) | SLC1A3SLC1A2SLC1A1ALPIPKM | |
| SCHEMBL2855957 | 0.80 | KMT2A (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3126205 | 0.80 | KMT2A (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3126212 | 0.80 | KMT2A (0.49) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL3225070 | 0.79 | KMT2A (0.50) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8797872 | 0.77 | NPC1 (0.49) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL8797866 | 0.77 | NPC1 (0.49) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL7469312 | 0.77 | NPC1 (0.49) | MEN1KMT2ANPC1RAB9ACA12 | |
| SCHEMBL3272399 | 0.76 | NPC1 (0.44) | MEN1KMT2ACYP1A2NPC1RAB9A | |
| SCHEMBL28215882 | 0.75 | CA12 (0.42) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106074474-A | Application of hydroxybenzyl serine hydrazine and pharmaceutically acceptable salts thereof in preparation of antitumor drugs | 中南大学湘雅医院 | 2016-11-09 | — | — | CN | disclosed |
| CN-106074474-A | Application of hydroxybenzyl serine hydrazine and pharmaceutically acceptable salts thereof in preparation of antitumor drugs | 中南大学湘雅医院 | 2016-11-09 | — | — | CN | disclosed |