Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL28110004 | 0.96 | SLC1A3 (0.42) | CYP1A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3126205 | 0.83 | KMT2A (0.49) | CYP1A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL2855957 | 0.83 | KMT2A (0.49) | CYP1A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3126212 | 0.83 | KMT2A (0.49) | CYP1A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL3225070 | 0.81 | KMT2A (0.50) | CYP1A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8797872 | 0.80 | NPC1 (0.49) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL7469312 | 0.80 | NPC1 (0.49) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL8797866 | 0.80 | NPC1 (0.49) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL3272399 | 0.79 | NPC1 (0.44) | CYP1A2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28215882 | 0.77 | CA12 (0.42) | CYP1A2KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110548150-B | Application of compound pharmaceutical composition in preparation of medicine for treating acute kidney injury | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |
| CN-110548150-A | Application of compound pharmaceutical composition in preparation of medicine for treating acute kidney injury | UNIV CHINA PHARMA | 2019-12-10 | — | — | CN | disclosed |