Ethylene

Ethylene

SCHEMBL28110102

C=C.C=CCC1(CC=C)c2ccccc2-c2ccc(CC(C)=O)cc21

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 12/20 0.42
PGR P06401 2/20 0.37
APEX1 P27695 1/20 0.36
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28110636 0.95 PDK2 (0.40) PDK2PGRAPEX1ALDH1A1MEN1
Toluene SCHEMBL28871777 0.94 PDK2 (0.38) PDK2PGRAPEX1ALDH1A1MEN1
SCHEMBL27757243 0.76 PDK2 (0.48) PDK2APEX1ALDH1A1
Alcohol SCHEMBL28110638 0.76 APEX1 (0.41) PDK2APEX1
SCHEMBL28649978 0.75 KDM4E (0.40) PDK2PGRAPEX1MAPT
SCHEMBL88451 0.75 PGR (0.49) PDK2PGRAPEX1ALDH1A1MEN1
SCHEMBL30511096 0.75 PGR (0.49) PDK2PGRAPEX1ALDH1A1MEN1
SCHEMBL28649404 0.74 POLB (0.39) PDK2PGRAPEX1POLBMAPT
Alcohol SCHEMBL28871387 0.74 PGR (0.43) PDK2PGRAPEX1ALDH1A1MEN1
SCHEMBL11759392 0.73 PDK2 (0.43) PDK2APEX1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106242938-A Fluorene ethylene derivative and synthetic method thereof 沈阳大学 2016-12-21 CN claimed
CN-106242938-B Fluorene ethylene derivative and synthetic method thereof 沈阳大学 2019-04-23 CN disclosed
CN-106242938-A Fluorene ethylene derivative and synthetic method thereof 沈阳大学 2016-12-21 CN disclosed