Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | STAT3 | P40763 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109720 | 0.91 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL28109719 | 0.87 | HDAC3 (0.64) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL1143516 | 0.82 | MEN1 (0.89) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL2825520 | 0.81 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL23297286 | 0.79 | POLB (0.63) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL26307648 | 0.78 | MEN1 (0.62) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL27687135 | 0.78 | MARS1 (0.65) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL26306719 | 0.78 | MAPT (0.57) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 | |
| SCHEMBL12122635 | 0.78 | TSHR (0.55) | SMN1; SMN2MAPTMEN1KMT2ALMNA | |
| SCHEMBL14132905 | 0.76 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTMEN1KMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106061975-A | Pyrazolo[1,5-a]pyrimidines as antiviral compounds | 阿波德穆斯公司 | 2016-10-26 | — | — | CN | claimed |
| CN-106061975-A | Pyrazolo[1,5-a]pyrimidines as antiviral compounds | 阿波德穆斯公司 | 2016-10-26 | — | — | CN | disclosed |